Entry-level biology courses, such as Bio100, serve as the first and often the only opportunity to introduce students to scientific inquiry and the use of scientific evidence in addressing personal, civic, and societal challenges. Thus, it is essential that Bio100 provides students with a strong foundation of biological knowledge together with the integrative problem-solving skills and global perspective necessary to address relevant real world challenges. To increase civic and social engagment, I have implemented a new curriculum that will facilitate investigation of societal challenges related to biology and enhance development of students’ civic and social responsibility. Students are expected to gain scientific literacy and a diverse set of skills and knowledge that will help them successfully integrate scientific perspectives into their own worldview. To assess student learning, I will utilize a pre- and post- Student Assessment of Learning Gains (SALG) tool to evaluate students' understanding, skills and attitudes, as well as the civic activities in which they engage.