The students apply knowledge obtained in lecture concerning genotype, mutations, and phenotype to an article about a mutant strain of Pseudomonas aeruginosa - a frequent cause of pneumonia in cystic fibrosis patients. Traditionally they struggle with two questions in particular. For Sp 09 the average on the hw was 60%. In F09 I when I handed out the assignment I gave them 5 min at the end of class to discuss the questions with their buddy. I told them I was NOT going to give any answers, it was just time for them to brainstorm with a partner. They completed the assignment outside of class and turned it in for the next lecture. The average was 73% and for Spring 10 the average was 82%. Interestingly, I had forgotten I did this (I think being div chair knocked it out of my brain) and for this semester (Sp13) the average was back to 64%. Last semester I had an SI (a really good ex-student) who would work with the students right after class when they recieved their hw. The average was 75%. This emphasizes the importance of working/studying right after obtaining information in the classroom.